Staphylococcal scalded skin syndrome affects males and females in equal numbers. Apr 05, 2018 staphylococcal scalded skin syndrome is a pathological condition usually found in children and immune compromised individuals caused due to bacteria staphylococcus aureus. The primary infection often begins during the first few days of life in the umbilical stump or diaper area. It rarely occurs in older people except for those with kidney failure or a weakened immune system. We present two cases of suspected inflicted burns, later diagnosed as staphylococcal scalded skin syndrome ssss. Staphylococcal scalded skin syndrome ssss or acute staphylococcal epidermolysis is an exfoliative skin disease and a toxin mediated staphylococcal infections affecting mostly neonates and adolescents and it is rare in adults 1, 2. Evidencebased information on staphylococcal scalded skin syndrome from hundreds of trustworthy sources for health and social care. Staphylococcal scalded skin syndrome ssss is a serious skin infection caused by the bacterium staphylococcus aureus. The bacteria produce a toxin that causes the skin damage. Ssss is caused by the release of two exotoxins epidermolytic toxins a and b from toxigenic strains of the bacteria staphylococcus aureus. This bacterium produces an exfoliative toxin that causes the outer layers of skin to blister and peel, as if theyve been doused with a hot liquid. Staphylococcal scalded skin syndrome skin disorders msd. Staphylococcal scalded skin syndrome microbiology society. Staphylococcal scalded skin syndrome information for parents.
These blisters can occur at areas of the skin away from the initial site. In small children, the syndrome has been associated with group 2 staphylococcal infection, as has previously been described in ritters disease. Staphylococcal scalded skin syndrome is a pathological condition usually found in children and immune compromised individuals caused due to bacteria staphylococcus aureus. Staphylococcal scalded skin syndrome is an acute epidermolysis caused by a staphylococcal toxin. Dec 01, 2017 staphylococcal scalded skin syndrome ssss is a serious skin infection caused by the bacterium staphylococcus aureus. Scalded skin syndrome sss is caused by infection with certain strains of staphylococcus bacteria. It causes a reddening and blistering of the skin that gives it a scalded or burned look. In this infection, skin surface of large parts of body gets peeled off and looks like burned skin by hot liquid. Etiology caused predominantly by phage group 2 staphylococci, particularly strains 71 and 55 found in nasopharynx and, less commonly, the umbilicus, urinary tract, a superficial abrasion, conjunctivae, and blood spreads hematogenously nelsons textbook of pediatrics. Staphylococcal scalded skin syndrome is a widespread painful rash caused by bacteria called staphylococcus aureus. When a toxinproducing type of staphylococcus aureus infects the skin, it can cause.
It is induced by two epidermiolytic toxins, a and b eta and etb produced by staphylococcus aureus. Learn about scalded skin syndrome from patients first hand experiences and trusted online health resources, including common treatments and medications. Staphylococcal scalded skin syndrome ssss in children. Staphylococcal scalded skin syndrome ssss is a recognised clinical entity that.
Staphylococcal scalded skin syndrome pictures, treatment. The scalded skin syndrome, or toxic epidermal necrolysis of lyell, is a nonspecific reaction pattern of the skin. If you think you or your child may have scalded skin syndrome, you should seek medical attention immediately. Staphylococcal scalded skin syndrome is caused by bacteria called staphylococcus aureus. Because skin helps protect us from infection, the condition also puts these patients at risk of developing sepsis, a bacterial infection of the bloodstream and body tissue source. Staphylococcal scalded skin syndrome ssss is a dermatological condition caused by staphylococcus aureus. A complete resolution of the condition can be expected within 10 days after the start of treatment without signs of any significant scarring. An 87year old female patient, with history of chronic obstructive pulmonary disease, was referred to our hospital with rash and septic shock. Dermatologic manifestations of staphylococcal scalded skin. It causes the skin to become red, sore and blistered. Although dukes identified it as a separate entity, it is thought not to be different from scarlet fever caused by staphylococcal exotoxin after keith powell proposed equating it with the condition currently known as staphylococcal scalded skin syndrome in 1979. Staphylococcal scalded skin syndrome is an infection of the skin.
Regular checkups following birth and during childhood years can allow for early detection of staphylococcal scalded skin syndrome. Ssss is a skin condition caused by toxic strains of the bacteria, staphylococcus aureaus that. Staphylococcal scalded skin syndrome dermatologic disorders. The diagnosis can be confirmed by a skin biopsy specimen, which can be expedited by frozen section processing, as staphylococcal scalded skin syndrome should be distinguished from life threatening toxic epidermal necrolysis. Staphylococcal scalded skin syndrome in a newborn a case. Staphylococcal scalded skin syndrome ssss refers to a spectrum of blistering skin diseases caused by s. Like other staphylococcal infections, staphylococcal scalded skin syndrome is contagious. Staphylococcal scalded skin syndrome after intraarticular. This condition is characterized by blistering in the skin surface which more or less looks like a burn and that is what gives it the name of staphylococcal scalded skin syndrome. It is known formally as staphylococcal scalded skin syndrome and as ritter disease. Staphylococcal scalded skin syndrome is caused by group ii coagulasepositive staphylococci, usually phage type 71, which elaborate exfoliatin also called epidermolysin, a toxin that splits the upper part of the epidermis just beneath the granular cell layer by targeting desmoglein1 see also staphylococcal infections. Staphylococcus aureus is the most frequent pathogen of septic arthritis. It looks like the skin has been scalded or burned by hot liquid.
Ssss usually presents with a prodrome of sore throat or. Staphylococcal scalded skin syndrome in a newborn a case report. Staphylococcal scalded skin syndrome ssss is the clinical term used for a spectrum of blistering skin diseases induced by the exfoliative epidermolytic toxins et of staphylococcus aureus. Staphylococcal scalded skin syndrome wissen fur mediziner.
One of the severe adverse effects of intraarticular injection in the knee is septic arthritis of the knee joint. Staphylococcal scalded skin syndrome causes, symptoms. Medical definition of staphylococcal scalded skin syndrome. Staphylococcal scalded skin syndrome ssss is a common disorder that is usually seen in infants and children and rarely seen in adults. Staphylococcal scalded skin syndrome altmeyers enzyklopadie. Apr 25, 2017 staphylococcal scalded skin syndrome ssss is a toxinmediated type of exfoliative dermatitis.
This bacterium produces an exfoliative toxin that causes the outer layers of. Aug 29, 2014 staphylococcal scalded skin syndrome ssss is characterised by red, blistered skin. Staphylococcal scalded skin syndrome tends to appear abruptly with diffuse erythema and fever. This newborn presented large erythematous, eroded, and oozing. Staphylococcal scalded skin syndrome definition of. Caused by a toxin emitted by the bacterium, rather than actual bacterial components, this syndrome leads to broad regions of exfoliating skin and is mainly observed in immunocompromised patients, newborns, infants and young children.
Dec 22, 2011 staphylococcal scalded skin syndrome ssss is an extensive desquamative erythematous condition of the skin characterised by blistering and epidermal peeling. Staphylococcal scalded skin syndrome l00 zuletzt aktualisiert am. Symptoms are widespread bullae with epidermal sloughing. Staphylococcal scalded skin syndrome ssss is an extensive desquamative erythematous condition of the skin characterised by blistering and epidermal peeling. Staphylococcal scalded skin syndrome ssss followup. What is staphylococcal scalded skin syndromecausessymptoms. Treatment is antistaphylococcal antibiotics and local. In staphylococcal scalded skin syndrome, there is an upper epidermal blister, whereas toxic epidermal necrolysis causes a dermalepidermal blister. Staphylococcal scalded skin syndrome medical definition. The staphylococcal scalded skin syndrome or the ritters disease1 is a staphylococcus aureus skin infection that typically has two periods of incidence. The disease occurs predominantly in children under 5 years of age. The damage creates blisters, as if the skin were scalded.
Jan 15, 2019 scalded skin syndrome is a bacterial infection that causes skin damage, leading to the skin peelingoff, which resembles a seconddegree burn the condition is caused by staphylococcus aureus bacteria, which produce a toxin that causes the skin to peeloff. Children scalded skin syndrome what is staphylococcal scalded skin syndrome. Staphylococcal scalded skin syndrome occurs almost exclusively in infants and children under the age of 6. Bacterial skin infection is a relatively frequent condition in paediatric population. The staphylococcal scalded skin syndrome may be a consequence of cellulitis, another skin infection. Scalded skin syndrome is a bacterial infection that causes skin damage, leading to the skin peelingoff, which resembles a seconddegree burn the condition is caused by staphylococcus aureus bacteria, which produce a toxin that causes the skin to peeloff. Mar 28, 2014 staphylococcal scalded skin syndrome 1.
In this infection, skin surface of large parts of body. Staphylococcal scalded skin syndrome definition staphylococcal scalded skin syndrome ssss is a disease, caused by a type of bacteria, in which large sheets of skin may peel. Staphylococcal scalded skin syndrome in a preterm newborn. We described a case of staphylococcal scalded skin syndrome in infant age of 21 days by discussing clinical and management issues. Although ssss is rarely observed in adults, the mortality rate is high in. Staphylococcal scalded skin syndrome prognosis most cases of ssss are mild, and the prognosis for children affected with this disorder is excellent. Staphylococcal scalded skin syndrome images dermnet nz.
Dec 27, 2018 read medical definition of syndrome, scalded skin. Staphylococcal scalded skin syndrome nord national. Staphylococcal scalded skin syndrome doccheck flexikon. Staphylococcal scalded skin syndrome evidence search nice. Staphylococcal scalded skin syndrome mimicking toxic epidermal necrolysis in a healthy adult tomoko oishi, yuka hanami, yasunobu kato, mikio otsuka, toshiyuki yamamoto. Staphylococcal scalded skin syndrome ssss is an illness characterised by red blistering skin that looks like a burn or scald, hence its name staphylococcal scalded skin syndrome. Staphylococcal scalded skin syndrome johns hopkins medicine. It is necessary to treat scalded skin syndrome with intravenous antibiotics and to protect the skin from allowing dehydration to occur if large areas peel off. Staphylococcal scalded skin syndrome ssss is a response to a staphylococcus staph infection. These exotoxins cause blisters to form and layers of skin to separate and slough off giving the appearance of severely burned skin source. Aug 31, 2016 staphylococcal scalded skin syndrome ssss is counted as one of the major skin infections. These blisters have the appearance of a scald or a burn, hence its name. Abstract staphylococcal scalded skin syndrome ssss, also known as ritter disease, and staphylococcal epidermal necrolysis, encompasses a spectrum of superficial blistering skin disorders caused by the.
Staphylococcal scalded skin syndrome ssss is a serious skin infection. Ssss is most common in infants and children, but can also affect adults with a depressed immune system or problems with kidney function. Pdf staphylococcal scalded skin syndrome in neonate. Staphylococcal scalded skin syndrome information for parents what is scalded skin syndrome. Ssss is caused by the release of two exotoxins epidermolytic toxins a and b from toxigenic strains of. The ability of the sds extract to neutralise or combine with et was. Staphylococcal scalded skin syndrome ssss is a potentially lethal complication of a staphylococcus aureus infection. The staphylococcal scalded skin syndrome is among the bacterial skin infections that cause blistering and skin exfoliation. The diagnosis of staphylococcal scalded skin syndrome ssss was clinically established and empiric therapy with vancomycin was started as well as supportive care with. Staphylococcal scalded skin syndrome ssss is counted as one of the major skin infections. The patient died 24 h after admission, after having developed multiple organ dysfunction syndrome.
Scalded skin syndrome is a skin reaction to a bacterial infection called staphylococcus aureus. This germ produces a toxin that causes the outer layer of the skin to be shed. The incidence, which has doubled in the last decade based on national hospitalization data, is estimated to be between. This disease usually occurs in children under 5 years old, especially in neonates with. Scalded skin syndrome risks, symptoms and leading causes. Staphylococcal scalded skin syndrome is caused by group ii coagulasepositive staphylococci, usually phage type 71, which elaborate exfoliatin also called epidermolysin, a toxin that splits the upper part of the epidermis just beneath the granular cell layer by targeting desmoglein1 see. Staphylococcal scalded skin syndrome ssss is a toxinmediated type of exfoliative dermatitis. Staphylococcal scalded skin syndrome ssss may also be called ritters disease. It is a rare condition, which tends to occur in younger children. What is staphylococcal scalded skin syndrome in children. Currently, the incidence of this disease is increasing in all ages. The infection causes peeling skin over large parts of the body.
772 1345 1062 165 77 1356 101 1243 792 871 1278 161 429 731 1053 304 1198 135 1290 178 1439 812 1009 1387 1073 1097 1025 1102 946 66 1056 1135 693